Drug metabolism plays a pivotal role in determining the pharmacokinetics and safety of medications. This book explores the various factors influencing drug metabolism, including genetic polymorphisms, enzyme induction and inhibition, age, diet, and disease states. It deals with the biochemical pathways of phase I and phase II metabolism, highlighting the role of cytochrome P450 enzymes and other key metabolic enzymes. Designed for pharmacologists, toxicologists, and healthcare professionals, the book provides a thorough understanding of the complexities involved in drug metabolism and its implications for therapeutic outcomes.
Mason Arnold is a leading dermatologist specializing in the factors affecting drug metabolism, focusing on how various biological and environmental factors influence the processing of dermatological medications in the body. His research investigates the roles of genetics, age, liver function, and concurrent medications in altering the metabolism and efficacy of skin treatments. Mason has published extensively on personalized pharmacological approaches that consider individual metabolic differences to optimize dermatological therapy outcomes. He has developed comprehensive metabolism assessment protocols that inform personalized treatment plans.