Liver and kidney diseases significantly affect drug kinetics, altering the absorption, distribution, metabolism, and excretion of medications. This book provides a comprehensive analysis of how hepatic and renal impairments influence drug pharmacokinetics. It covers dosage adjustments, drug selection considerations, and the management of polypharmacy in patients with liver and kidney dysfunction. Designed for clinicians, pharmacists, and pharmacologists, the book offers practical guidance for optimizing drug therapy in populations with compromised liver and kidney function.
Sophia Jordan is an expert dermatologist specializing in drug kinetics in liver and kidney disease, focusing on how hepatic and renal impairments affect the pharmacokinetics of dermatological medications. Her research explores the altered absorption, distribution, metabolism, and excretion of drugs in patients with compromised liver and kidney function, impacting treatment efficacy and safety. Sophia has authored numerous studies on adjusting dermatological drug dosages and selecting appropriate therapies for patients with liver and kidney diseases to prevent toxicity and optimize outcomes. She has developed comprehensive drug kinetics protocols that inform safe prescribing practices for patients with renal and hepatic impairments.