Genetic variability is a key determinant of individual responses to drug therapy. This book investigates how genetic differences influence drug metabolism, efficacy, and the risk of adverse effects. It covers topics such as pharmacogenomics, single nucleotide polymorphisms (SNPs), and the role of specific genes in drug transport and receptor function. Designed for geneticists, pharmacologists, and personalized medicine practitioners, the book highlights the importance of integrating genetic information into clinical decision-making to enhance personalized therapy.
Ava Alexander is a leading dermatologist specializing in the impact of genetic variability on drug response, focusing on how genetic differences among individuals influence their reactions to dermatological medications. Her research explores the role of genetic polymorphisms in drug-metabolizing enzymes, transporters, and receptors, affecting the efficacy and safety of treatments for skin conditions. Ava has authored numerous studies on personalized pharmacogenomic approaches to optimize dermatological therapy based on genetic profiles, enhancing treatment outcomes and minimizing adverse effects. She has developed comprehensive pharmacogenomic protocols that inform personalized treatment plans based on genetic insights. She also provides comprehensive guidelines and insights for clinicians to incorporate genetic variability assessments into their prescribing practices, promoting personalized and effective dermatological care through genetic-informed pharmacological approaches.