Biologics represent a rapidly growing class of therapeutics with unique pharmacokinetic and pharmacodynamic profiles. This book provides an in-depth exploration of the pharmacokinetics and pharmacodynamics of biologic drugs, including monoclonal antibodies, cytokines, and cell-based therapies. It discusses factors affecting their absorption, distribution, metabolism, and excretion, as well as their specific mechanisms of action and interactions with biological targets. Aimed at pharmaceutical scientists, pharmacologists, and healthcare professionals, the book offers comprehensive insights into the development and clinical application of biologic therapies.
Logan Hamilton is an expert dermatologist specializing in the pharmacokinetics and pharmacodynamics of biologics, focusing on understanding how these advanced therapeutic agents are processed in the body and interact with biological targets in dermatological treatments. His research investigates the absorption, distribution, metabolism, and excretion of biologics, as well as their mechanisms of action in treating complex skin conditions like psoriasis, atopic dermatitis, and hidradenitis suppurativa. Logan has published extensively on optimizing dosing regimens and enhancing the efficacy of biologic therapies through a deep understanding of their pharmacokinetic and pharmacodynamic profiles. He has developed comprehensive pharmacokinetic and pharmacodynamic protocols that inform the optimal use of biologics in dermatological care. He also offers valuable insights and guidelines for clinicians to effectively utilize biologics in their dermatological practice, ensuring safe and personalized treatment approaches based on comprehensive pharmacological knowledge.