Elderly patients often present unique challenges in pharmacotherapy due to physiological changes associated with aging. This book examines the pharmacokinetic considerations critical to effective and safe drug therapy in the elderly, including alterations in drug absorption, distribution, metabolism, and excretion. It explores the impact of comorbidities, polypharmacy, and age-related physiological changes on drug kinetics and pharmacodynamics. Aimed at geriatricians, pharmacists, and healthcare providers, the book provides strategies for dose optimization, minimizing adverse effects, and enhancing therapeutic outcomes in the aging population.
Grace Cole is a Clinical Pharmacologist in the Geriatric Medicine Division at Springfield University. She has published more than 80 research papers on pharmacokinetics and drug metabolism in elderly populations. Grace’s work emphasizes optimizing medication regimens to improve efficacy and reduce adverse effects in older adults. She has edited two comprehensive volumes on pharmacokinetic principles and their application in geriatric pharmacotherapy.