Tumor biology explores the underlying mechanisms that transform normal cells into cancerous ones, shedding light on malignancy development. This book explains the molecular, genetic, and cellular basis of neoplasia, including oncogene activation, tumor suppressor gene loss, and microenvironmental influences. Topics such as tumor angiogenesis, invasion, and metastasis are addressed with diagrams and clinical examples. It bridges basic science with clinical oncology, highlighting biomarkers, therapeutic targets, and resistance mechanisms. Case scenarios and molecular profiles illustrate how biological insights influence diagnosis and treatment. The content is essential for understanding the pathogenesis and progression of neoplastic diseases.
Blythe Knowles is a cancer biology researcher with specialized training in tumor progression, oncogenes, and molecular drivers of neoplasia. She leads translational research projects aiming to bridge experimental oncology with clinical applications. Her extensive bibliography includes studies on tumor markers, cell cycle deregulation, and targeted therapies. She frequently collaborates with biotech firms and research institutions to improve diagnostic accuracy. Her mentoring of postgraduate fellows in tumor pathology and molecular methods is well respected.